Cervical Cancer is responsible for more than any gynecologic-related deaths worldwide than any other malady, making it the most important preventable disease in women's health today. Worldwide each year 4, 93,243 women are diagnosed with cervical cancer of whom 2,40,000 women die of this disease (WHO).
Kenya contributes more than ¼ of the global burden. Each year about 1,32,082 cases of this cancer are diagnosed and more than 74,118 women die of this disease, this cancer being the most common cancer of women in our country. You may get complete information about cervical cancer prevention and treatment online.
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Human Papilloma Virus (HPV) infection is now a well-established cause of cervical cancer. Human papillomavirus is a double-stranded DNA virus of the papovavirus family. More than 100 types described; 30 infect anogenital tract.
High risk types of 16, 18, 31, 33, 35, 45, 51, 52, 56, 58, 59 and 68 are associated with neoplasia. HPV 16 and 18 in 70% of these cancer cases worldwide and 45 and 31 with a further 10% of this cancer case.
Though HPV is a necessary cause of cervical cancer but is not a sufficient cause. Other Cofactors are necessary for progression from cervical HPV infection to cancer.
High parity, tobacco smoking, longterm use of oral contraceptives and coinfection with HIV have been identified as established co-factors; co-infection with chlamydia trachomatis and herpes simplex virus type -2, immunosuppression and certain dietary deficiencies are other probable co-factor.